June, 2016: We published paper “Glyco-genes change expression in cancer through aberrant methylation” in a special issue of BBA General Subjects “Glycans in personalised medicine”. In this work we:
- identified glyco-genes that show changed expression and methylation in different types of cancer;
- showed that a subset of ten glyco-genes consistently show both aberrant expression and CpG methylation;
- showed that some of the identified genes show potential as prognostic markers in certain types of cancer.
The cover-page of this special issue presents our Venn diagrams which show the number of overlapping genes found as the most differentially methylated or the most differentially expressed in hepatocellular carcinoma, breast cancer, cervical cancer and melanoma.